研究领域
(1)细菌真菌互作;(2)真菌致病机理研究;(3)真菌病害生物防治
学习经历
2013.09-2019.12,博士,植物病理学,华南农业大学
2009.09-2013.06,学士,植物保护,华南农业大学
工作经历
2023.09-至今,研究人员,群体微生物研究中心,华南农业大学
2020.01-2023.09,博士后, 群体微生物研究中心,华南农业大学
发表论文
Liang Zhibin#, Huang Luhao#, Liu Huidi#, Zheng Ying, Feng Jiani, Shi Zurong, Chen Yufan, Lv Mingfa, Zhou Jianuan, Zhang Lian-Hui*, Chen Shaohua*. Characterization of the Arn lipopolysaccharide modification system essential for zeamine resistance unveils its new roles in Dickeya oryzae physiology and virulence. Molecular Plant Pathology, 2023.
Liang Zhibin#, Lin Qiqi#, Wang Qingwei#, Huang Luhao, Liu Huidi, Shi Zurong, Cui Zining, Zhou Xiaofan, Gao Yong-Gui, Zhou Jianuan, Zhang Lian-Hui*, Deng Yizhen*. Gram-negative bacteria resist antimicrobial agents by a DzrR-mediated envelope stress response. BMC Biology, 2023, 21(1):62.
Lv Mingfa#, Ye Sixuan#, Hu Ming, Xue Yang, Liang Zhibin, Zhou Xiaofan, Zhang Lianhui*, Zhou Jianuan*. Two-component system ArcBA modulates cell motility and biofilm formation in Dickeya oryzae. Frontiers in Plant Science, 2022, 13:1033192.
Lin Qiqi#, Wang Huishan#, Huang Jiahui, Chen Qunyi, Yu Guohui, Xu Zeling, Cheng Ping, Liang Zhibin*, Zhang Liang-Hui*. Spermidine is an intercellular signal modulating T3SS expression in Pseudomonas aeruginosa. Microbiology Spectrum, 2022:e64422.
Chen Yufan#, Lv Mingfa#, Liang Zhibin, Liu Zhiqing, Zhou Jianuan*, Zhang Lian-Hui*. Cyclic di-GMP modulates sessile-motile phenotypes and virulence in Dickeya oryzae via two PilZ domain receptors. Molecular Plant Pathology, 2022, 23(6):870-884.
Shi Zurong#, Wang Qingwei#, Wang Shunchang, Wang Chengrun, Zhang Lian-Hui*, Liang Zhibin*. Hfq is a critical modulator of pathogenicity of Dickeya oryzae in rice seeds and potato tubers. Microorganisms, 2022, 10(5):1031.
Liang Zhibin, Liu Huidi, Xu Zeling, Zhang Lian-Hui*. First report of Pectobacterium aroidearum causing soft rot in olecranon honey peach (Prunus persica) in China. Plant Disease, 2022, 106(6).
Chen Yufan#, Li Yanchang#, Zhu Minya#, Lv Mingfa, Liu Zhiqing, Chen Zhongqiao, Huang Ying, Gu Weihan, Liang Zhibin, Chang Changqing, Zhou Jianuan, Zhang Lian-Hui*, Liu Qiongguang*. The GacA-GacS type two-component system modulates the pathogenicity of Dickeya oryzae EC1 mainly by regulating the production of zeamines. Molecular Plant-Microbe Interactions, 2022, 35(5):369-379.
Chen Yufan#, Zhou Jianuan#, Lv Mingfa, Liang Zhibin, Parsek Matthew R*, Zhang Lian-Hui*. Systematic analysis of c-di-GMP signaling mechanisms and biological functions in Dickeya zeae EC1, mBio, 2020, 11(6):e02993-20.
Liu Shiyin, He Fei, Lin Nuoqiao, Chen Yumei, Liang Zhibin, Liao Lisheng, Lv Mingfa, Chen Yufan, Chen Shaohua, Zhou Jianuan*, Zhang Lian-Hui*. Pseudomonas sp. ST4 produces variety of active compounds to interfere fungal sexual mating and hyphal growth., Microbial Biotechnology, 2020, 13(1):107-117.
Liang Zhibin, Huang Luhao, He Fei, Zhou Xiaofan, Shi Zurong, Zhou Jianuan, Chen Yufan, Lv Mingfa, Chen Yumei, Zhang Lian-Hui*. A substrate-activated efflux pump, DesABC, confers zeamine resistance to Dickeya zeae, mBio, 2019, 10(3):e00713-19.
Lv Mingfa, Chen Yufan, Liao Lisheng, Liang Zhibin, Shi Zurong, Tang Yingxin, Ye Sixuan, Zhou Jianuan*, Zhang Lianhui*. Fis is a global regulator critical for modulation of virulence factor production and pathogenicity of Dickeya zeae, Scientific Reports, 2018, 8:341.
Chen Yu-Mei, Dong Yi-Hu, Liang Zhi-Bin, Zhang Lian-Hui*, Deng Yi-Zhen*. Enhanced vascular activity of a new chimeric promoter containing the full CaMV 35S promoter and the plant XYLOGEN PROTEIN 1 promoter, 3 Biotech, 2018, 8(9):380.
科研项目
1. 国家自然科学基金青年项目(32000085):玉米迪基氏菌对抗生素zeamines的抗性调控机理研究。2021年1月1日-2023年12月31日,在研,项目主持人。
2. 广东省区域联合基金-青年基金项目(2020A1515110465):玉米迪基氏菌ArnBCADTEF基因簇介导的zeamines抗性机制研究。2020年10月1日至2022年6月30日,结题,项目主持人。
3. 国家自然科学基金联合基金项目(U22A20480):重要作物土传性细菌软腐病致病成灾与抗病机制研究。2023年1月1日至2026年12月31日,在研,项目主要参与人(排名第三)。
4. 国家自然科学基金面上项目(32072450):水稻白叶枯病菌III型分泌系统抑制剂作用靶标的发现与互作机制的研究。2021年1月1日-2024年12月31日,在研,项目主要参与人(排名第二)。