Education
2013.09-2019.12 Ph.D., Plant Pathology, South China Agricultural University
2009.09-2013.06 B.Sc., Plant Protection, South China Agricultural University
Professional Experience
2023.09-present Principal investigator, Integrative Microbiology Research Center, South China Agricultural University
2020.01-2023.09 Postdoctoral Fellow, Integrative Microbiology Research Center, South China Agricultural University
Research Interest
My current interest is the cross-kingdom interaction between environmental bacteria and the plant pathogenic fungi Magnaporthe oryzae and Sporisorium scitamineum in microbial communities. Magnaporthe oryzae and Sporisorium scitamineum can cause severe losses in rice and sugarace production. I want to know how enviromental bacteria act during disease development caused by Magnaporthe oryzae or Sporisorium scitamineum infection, how Magnaporthe oryzae and Sporisorium scitamineum response to the environmental changes caused by environmental bacteria, and how to exploit the synthetic microbial communities (SynComs) to control rice blast and sugarcane smut caused by Magnaporthe oryzae and Sporisorium scitamineum. I have published more than 10 papers in peer-viewed journals focusing on the regulation of bacterial virulence-related physiology and antimicrobial resistance. I have been the principal or co-investigator on research grants supported by National Natural Science Foundation of China and Guangdong Basic and Applied Basic Research Foundation.
Publications
1. Liang Zhibin#, Huang Luhao#, Liu Huidi#, Zheng Ying, Feng Jiani, Shi Zurong, Chen Yufan, Lv Mingfa, Zhou Jianuan, Zhang Lian-Hui*, Chen Shaohua*. Characterization of the Arn lipopolysaccharide modification system essential for zeamine resistance unveils its new roles in Dickeya oryzae physiology and virulence. Molecular Plant Pathology, 2023.
2. Liang Zhibin#, Lin Qiqi#, Wang Qingwei#, Huang Luhao, Liu Huidi, Shi Zurong, Cui Zining, Zhou Xiaofan, Gao Yong-Gui, Zhou Jianuan, Zhang Lian-Hui*, Deng Yizhen*. Gram-negative bacteria resist antimicrobial agents by a DzrR-mediated envelope stress response. BMC Biology, 2023, 21(1):62.
3. Lv Mingfa#, Ye Sixuan#, Hu Ming, Xue Yang, Liang Zhibin, Zhou Xiaofan, Zhang Lianhui*, Zhou Jianuan*. Two-component system ArcBA modulates cell motility and biofilm formation in Dickeya oryzae. Frontiers in Plant Science, 2022, 13:1033192.
4. Lin Qiqi#, Wang Huishan#, Huang Jiahui, Chen Qunyi, Yu Guohui, Xu Zeling, Cheng Ping, Liang Zhibin*, Zhang Liang-Hui*. Spermidine is an intercellular signal modulating T3SS expression in Pseudomonas aeruginosa. Microbiology Spectrum, 2022:e64422.
5. Chen Yufan#, Lv Mingfa#, Liang Zhibin, Liu Zhiqing, Zhou Jianuan*, Zhang Lian-Hui*. Cyclic di-GMP modulates sessile-motile phenotypes and virulence in Dickeya oryzae via two PilZ domain receptors. Molecular Plant Pathology, 2022, 23(6):870-884.
6. Shi Zurong#, Wang Qingwei#, Wang Shunchang, Wang Chengrun, Zhang Lian-Hui*, Liang Zhibin*. Hfq is a critical modulator of pathogenicity of Dickeya oryzae in rice seeds and potato tubers. Microorganisms, 2022, 10(5):1031.
7. Liang Zhibin, Liu Huidi, Xu Zeling, Zhang Lian-Hui*. First report of Pectobacterium aroidearum causing soft rot in olecranon honey peach (Prunus persica) in China. Plant Disease, 2022, 106(6).
8. Chen Yufan#, Li Yanchang#, Zhu Minya#, Lv Mingfa, Liu Zhiqing, Chen Zhongqiao, Huang Ying, Gu Weihan, Liang Zhibin, Chang Changqing, Zhou Jianuan, Zhang Lian-Hui*, Liu Qiongguang*. The GacA-GacS type two-component system modulates the pathogenicity of Dickeya oryzae EC1 mainly by regulating the production of zeamines. Molecular Plant-Microbe Interactions, 2022, 35(5):369-379.
9. Chen Yufan#, Zhou Jianuan#, Lv Mingfa, Liang Zhibin, Parsek Matthew R*, Zhang Lian-Hui*. Systematic analysis of c-di-GMP signaling mechanisms and biological functions in Dickeya zeae EC1, mBio, 2020, 11(6):e02993-20.
10. Liu Shiyin, He Fei, Lin Nuoqiao, Chen Yumei, Liang Zhibin, Liao Lisheng, Lv Mingfa, Chen Yufan, Chen Shaohua, Zhou Jianuan*, Zhang Lian-Hui*. Pseudomonas sp. ST4 produces variety of active compounds to interfere fungal sexual mating and hyphal growth., Microbial Biotechnology, 2020, 13(1):107-117.
11. Liang Zhibin, Huang Luhao, He Fei, Zhou Xiaofan, Shi Zurong, Zhou Jianuan, Chen Yufan, Lv Mingfa, Chen Yumei, Zhang Lian-Hui*. A substrate-activated efflux pump, DesABC, confers zeamine resistance to Dickeya zeae, mBio, 2019, 10(3):e00713-19.
12. Lv Mingfa, Chen Yufan, Liao Lisheng, Liang Zhibin, Shi Zurong, Tang Yingxin, Ye Sixuan, Zhou Jianuan*, Zhang Lianhui*. Fis is a global regulator critical for modulation of virulence factor production and pathogenicity of Dickeya zeae,Scientific Reports, 2018, 8:341.
13. Chen Yu-Mei, Dong Yi-Hu, Liang Zhi-Bin, Zhang Lian-Hui*, Deng Yi-Zhen*. Enhanced vascular activity of a new chimeric promoter containing the full CaMV 35S promoter and the plant XYLOGEN PROTEIN 1 promoter, 3 Biotech, 2018, 8(9):380.